Damage reduction order?

Say you had a rapturous ghoul which reduces damage from attacks by 25% and holy defiance level 1. If your creature is hit for originally 500 damage and they have 800 hp, does the end result being 375 or 292?

The reduction from the Rapturous Ghoul would come first, and if the damage is still over Holy Defiance’s threshold then it would be reduced to that.