Poison: Much more effective on lower floors. May be ineffective on higher floors. Initial impression that base Attack stats (28/22 for Noxious/Necropolis) may cause trouble.
Burn: Viable, depending on mechanics. Inflictor base stats are 34/32/28 (Flamegrip/Magma Golem/Scourge Mummy). Catching Fire buff helps as well.
Disease/Infection: Plaguebearer much more viable now that you can make a full-Topaz Nether and have both status scale off its stats. Ghoul’s Grip no longer a one-shot kill (necessary debuff). Pestilent Smog is now horrible (base 8 speed/ 10 luck).
Minotaur Skullcrusher: Bad now. Lost sustainabilty.
Moltenarmor: Hallelujah, no more threat of instant death from Flaring Efreet on early floors! Totally necessary debuff.
Jinx: Good stuff, more stat-based, along with other patch changes making Luck a real build type now.
Does status damage scale with the initial stack creator’s Attack or the attack of the latest inflictor? The latter will make Moon Hunter / Flamegrip much more viable.
HP continues to be indirectly debuffed - now HP boosts are pretty much meaningless except for Frostfire/Redeemer builds. Alcazar/Proliferator are much better; Carnage Antagonizer sucks (base 28 attack and attack-based ability). Luck builds improved with Reroute to Remain/Mirror’s Truth buff. Brownie Mauler mildly buffed.
Sorcery builds buffed heavily; improved Rain of Embers / Cosmic Wrath / Soulburn / Suffocation now based off of caster Spellpower, which improves dedicated caster builds tremendously. Probably needs some effect that boosts Spellpower to be made most effective.
Smog creatures suck now, casters FTW. Everybody on the Alcazar wagon!
Overall Rating: GOOD STUFF, rebalancing most builds on a level with each other.